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 ISSN: 0973- 3809 

 

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VOLUME 3 : Number  2: (May – August 2001)

Abstracts 

>>>>Editorial Review

Cost-Effective Management of Drug Resistance in Pulmonary Medicine
Sudheendra Ghosh.C, Professor and Head, Dept.of Respiratory Medicine,  Medical College, Trivandrum

        The changing spectrum of the host and the emergence of new and drug resistant organisms complicate management of pulmonary infections. Drug resistance to microorganism has become a world wide problem. Drug resistance is defined as the temporary or permanent capacity of the organisms or their progeny to remain viable or multiply in the presence of the concentration of the drug that would normally destroy or inhibit the growth of their cells. Resistance among respiratory pathogens has increased since 1970s. Ampicillin resistant H.influenzae have increased and now are common many parts of the world. After World War II, penicillin resistant among gonococci and staphylo coccal strains was first noted. Methicillin resistant Staphylococcus aureus (MRSA) emerged in the 1970s. Aminoglycoside resistant pseudomonas aeroginosa was first noted after the widespread use of gentamicin. Ceftazidime resistant and ciprofloxacin resistant P.aeroginosa remain a concern today. Resistance to anti-tuberculosis drugs was noticed immediately after the introduction of streptomycin. Reported drug resistance in India shows initial drug resistance 18.5% for INH, 0.6% for RMP and acquired resistance 50.7% for INH and 33.3% for RMP.

          There is no resistance among atypical pulmonary pathogens (e.g., Legionella, Mycoplasma pneumoniae, Chlamydia pneumoniae, Q fever, tularemia, or psittacosis)> Bacteroids fragilis and anaerobic organisms, in general have not shown any clinically significant resistance. Acinetobacter is reported in the literature as highly resistant or multi resistant to several antibiotics.

>>>>Review Article 

Radiological Imaging in Bronchiectasis
Gupta KB, Sanjeev  Tandon, Monika Tandon,
Department of Tuberculosis and Chest Diseases,          Pt.B.D.Sharma Post Graduate Institute of Medical Sciences,  Rohtak, Haryana.

Bronchiectasis remains an important and relatively common cause of pulmonary disability. HRCT is the imaging method of choice after standard chest radiography and bronchography for examining patients with suspected bronchiectasis and is an accurate procedure in the recognition of bronchiectasis especially in patients with clinical symptoms but a normal chest radiograph.

>>> Leading Article

Allergen Immunotherapy : When to Start and When to Stop[No abstract available] 
 Balakrishnan Menon, MPS Menon, VP Chest Institute, University of Delhi, Dehi

>>>>Original Paper

Pneumothorax – An Analysis of 110 Cases
 Remshchandra Babu KM, Jovin John Mathew, Santhosh Kumar P.V, James P.T. Institute of Chest Diseases, Medical College, Calicut.

Abstract: 

Objective: To study the cases of pneumothorax managed in a respiratory medicine department of a tertiary care centre. 

Design: A retrospective study 

Setting: Institute of Chest Diseases, Calicut Medical College, Kozhikode. 

Period of study: January 1999 to December 2000 

Patients and methods: Records of 110 patients with pneumothorax were reviewed and analysed. 

Results: Males constituted 86% of the 110 cases studied. Primary spontaneous pneumothorax occurred in 16% of the patients, secondary spontaneous pneumothorax in 75% and traumatic pneumothorax consistuted 9% of the cases of which 90% were iatrogenic. Primary spontaneous pneumothorax was found on the right side twice that on the left and mostly afflicted patients in their twenties. Intercostal drainage was done in 55% of the 18 cases with primary spontaneous pneumothorax. Among those with secondary spontaneous pneumothorax, tuberculosis constituted the majority, followed by Chronic Obstructive Pulmonary Disease (COPD). Intercostal drainage had to be done in 52% of the 82 patients with secondary spontaneous pneumothorax. Traumatic pneumothorax was managed conservatively in all cases. Persistent pneumothorax constituted 28% of the patients. 

Conclusion: Males are afflicted more than female sin all categories of pneumothorax. Right-sided lesion outnumber left-sided ones. Conservative management was done in as many patients as in those in whom intervention in the form of intercostals drainage was done. Needle aspiration or drainage of the pleural space may be safely done in patients with significant pneumothorax, provided all parameters are stable.

>>>>Special Articles

Blood Transfusion in the Critically Ill Patients[No abstract available]
 
Jain P.K., Director, Dept.of Critical Care Medicine, Malabar Institute of Medical Sciences, Calicut, Kerala
 

Asthma Guideline – Simplified [No abstract available]
 
Ravindran C, Professor & Head, Dept.of TB & Chest Diseases, T.D.Medical College, Alappuzha

>>>> Case Reports

Leiomyoma of Trachea Presenting as Bronchial Asthma
 Ramachandran PV, Rauf CP*, Della Harigovind,       Neelakandhan KS**   KHRWS Imageology Centre & Chest Hospital*, Calicut     SCTIMST**, Thiruvananthapuram

Abstract:

           Tracheal tumors are often overlooked as a cause of pulmonary symptoms until they reach an advanced state. They often present with cough and wheeze, mimicking bronchial asthma. Most tracheal tumors in adults are cancerous (80% to 90%). Benign tracheal tumors are rare in adult patients. A case history of a 52 year old lady is presented with a rare tracheal leiomyoma. She was treated as having bronchial asthma initially. The possibility of the presence of an upper airway obstruction was not raised until the stridor was noted and the flow-volume loop testing suggested the former. A simple investigation like a plain lateral view X-ray of soft tissues of neck revealed an intratracheal mass. Bronchoscopy and helical computed tomography with multiplanar reconstructions and virtual endoscopy confirmed the diagnosis of upper airway obstruction caused by a tracheal tumor. Surgical resection and end-to-end anastomosis was performed.

An Unusual Cause of Dysphagia and Stridor
Ravindran C,Professor & Head, Dept.of TB & Chest Diseases,T.D.Medical College, Alappuzha

Bronchogenic carcinoma by itself or through metastatic mediastal lymphadenopathy may involved esophagus. Oesophageal displacement is rather common that is functional compromise. Here a case being reported of a 91 year old female patient who initially presented with dysphagia for which an oesophageal stent was applied. Subsequently, patient developed stridor, the cause of which is partly attributed to compression of posterior wall of trachea by stent.

>>>> From the Book of Medical practice

Doctor-Patient Rapport / Relationship
Sarma O.A.

 

 

 

 

PULMON - The Journal of respiratory Sciences